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KMID : 0390320160260010041
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Chungbuk Medical Journal
2016 Volume.26 No. 1 p.41 ~ p.52
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Frequency and Antimicrobial Susceptibility of Microorganism Isolated from Chungbuk National University Hospital during 2014 Year
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Son Bo-Ra
Shin Kyeong-Seob
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Abstract
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Purpose : The periodic analysis of frequency and antimicrobial susceptibility of the isolates can provide clinicians with the important information for the empirically antibiotic treatment of the infected patients. In this study, we analyzed the blood culture results of Chungbuk National University hospital during 2014 years.
Materials and Methods : The culture results of Chungbuk National University hospital (CBNUH) during 2014 years were analysed to determine the species and antimicrobial susceptibility of the isolates, retrospectively. Blood culture bottles were incubated in the Bact/Alert 3D system (bioMerieux Inc., Durham, NC, USA), and then the isolates were identified by the VITEK II system. Antimicrobial susceptibility of microorganisms was tested by the VITEK II system (bioMerieux Inc., Hazelwood, MO, USA) or disk diffusion method by Clinical and Laboratory Standards Institute guideline.
Results : The number of positive culture was 8,321 (of 50,505, 16.26%). Frequently isolated organisms in decreasing order were Escherichia coli (20.7%), Staphylococcus aureus (11.7%), Enterococcus faecium (8.11%), Klebsiella pneumoniae (7.38%), Acinetobacter baumannii (6.6%), Enterococcus faecalis (6.43%), Pseudomonas aeruginosa (5.71%). During 2014 year, the isolation rate of methicillin-resistant S. aureus (MRSA), and vancomcyin-resistant Enterococci (VRE) were isolated to 68% and 37%, respectively. Moreover the proportion of extended-spectrum β-lactamase (ESBL) producing E. coli and K. pneumoniae were isolated to 23% and 25%, respectively. Imipenem resistant P. aeruginosa and A. baumannii were 21% and 81%.
Conclusions : During 2014 year, the frequent microorganisms isolated from CBNUH in decreasing order were E. coli, S. aureus, E. fafecim and K. pneumoniae. Isolation rates of MRSA, VRE, ESBL, and multi-resistant non-fermenting gram negative bacilli had been increased. It seems to be necessary to enhance infection control for multi-resistant microorganisms as well as to use the proper antibiotics by the antimicrobial susceptibility testing.
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KEYWORD
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Species, Antimicrobial susceptibility testing, Isolation rate, Resistant rate
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